Pancreatic Cancer Screening Study

PANDOME Study

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Diabetes and pancreatic cancer: What is the connection?

  • What is the purpose of the study?

    The PANDOME study aims to detect pancreatic cancer in its earliest stages by using magnetic resonance imaging (MRI). Individuals with new-onset diabetes (NOD) and over 50 years of age have an approximate eight-fold risk of developing pancreatic cancer within two years of a diabetes diagnosis. Individuals who have diabetes that seems difficult to control (HbA1c increase of >2%), or deteriorating diabetes (DD), are also at increased risk for pancreatic cancer. Although this phenomenon is widely recognized by clinicians, additional research is needed. The goal of the study is to determine which individuals with NOD or DD are at risk.

  • Are you eligible to participate?
    • Are you at least 50 years of age?
    • Have you been diagnosed with diabetes within the past 12 months or has your long-standing diabetes become difficult to control recently?
    • Are you able to undergo an MRI?
  • What is the study plan?
    If enrolled in the trial, you will undergo a magnetic resonance imaging (MRI) scan of the pancreas. Research staff will also evaluate your overall health every 6 months and obtain a blood sample for research purposes. Before participation, risks and benefits will be explained in detail during a process called informed consent.
  • Who will pay for the MRI tests and other study procedures?
    Nuvance Health will cover the costs of MRI examinations AND other study related costs through philanthropic donations.
  • Is this study being performed at other centers?
    Yale University is now included as a study center, and will be recruiting participants soon.
  • Who is leading the study?
    The principal investigators of the study include Richard Frank, MD, director of cancer research at Nuvance Health and James Farrell, MD, at Yale University.

Are you eligible to participate?


I
f you would like to see if you are eligible to participate in the PANDOME cancer screening study, please complete the form.


For questions or additional information contact Tammy Lo, APRN at (203) 855-3551 or tammy.lo@nuvancehealth.org.

Cindy's journey: From uncontrolled diabetes to early pancreatic cancer detection and hope

The 82-year-old from Fairfield County, Connecticut, felt both overwhelmed by her pancreatic cancer diagnosis and grateful to have participated in a study that led to its early detection—a rare occurrence for this type of cancer.